The road less taken: less appreciated pathways for manipulating cd8+ t cell exhaustion

HIGHLIGHTS

  • who: Andrea C. Pichler et al. from the Laboratory of Immune System Biology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, MD, United States The Ohio State University have published the article: The Road Less Taken: Less Appreciated Pathways for Manipulating CD8+ T Cell Exhaustion, in the Journal: (JOURNAL)
  • what: In this review, the authors focus on some less-appreciated pathways affecting the development of T_cell exhaustion.
  • future: While the success of immune-based therapies has been striking the successful implementation in only a fraction of cancers argues that new . . .

     

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