The role and regulatory mechanism of m a methylation in the nervous system

HIGHLIGHTS

  • who: . and colleagues from the Harvard Medical School, United States University of Texas Southwestern have published the research work: The role and regulatory mechanism of m A methylation in the nervous system, in the Journal: (JOURNAL)

SUMMARY

    Epigenetic modification is the regulation of gene_expression through a series of complex modifications without changing the gene sequence, and mainly includes DNA modification, RNA modification, histone modification, and chromatin remodeling (Jones et_al, 2016). Different types of RNA modifications have been identified, including N6-methyladenosine (m6A) (Dominissini et_al, 2012), 5-methylcytidine (m5c) (Edelheit et_al, 2013) and N1methyladenosine . . .

     

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