HIGHLIGHTS
- who: ufeffRichard J.ufeff ufeffElsworthyufeff and colleagues from the Johannes Gutenberg University Mainz, Germany have published the research: The role of ADAM10 in astrocytes: Implications for Alzheimeru2019s disease, in the Journal: (JOURNAL)
- what: Much of this research is focused on ADAM10 and cytokine signaling, where stimulation of astrocytes with frontiersin.org 10.3389/fnagi.2022.1056507 proinflammatory mediators have been shown to induce ADAM10 ectodomain shedding.
SUMMARY
There is evidence to the contrary, such as the presence of Aβ in cognitively healthy individuals, and the lack of correlation between amyloid plaque . . .
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