The role of autophagy in cadmium-induced acute toxicity in glomerular mesangial cells and tracking polyubiquitination of cytoplasmic p53 as a biomarker

HIGHLIGHTS

• who: Ki-Tae Jung from the Animal experiments and Cd injection The animal care and Cd injection procedures were performed as previously described Briefly, week-old male C BL/, (C57) mice (Orientbio, Seongnam, South Korea) were kept under regular conditions with , h light-dark cycles at, % humidity. The animals were randomly divided into two groups of eight mice each. The mice were treated with cadmium acetate (, mg/kg body weight) or an equivalent volume of saline via intraperitoneal (i.p.) injections for , weeks. The animals were then anesthetized with, % isoflurane in oxygen. The animal experiments were conducted . . .
  

   

  

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