HIGHLIGHTS
- who: Rongying Tan from the des Cordeliers (CRC), France have published the paper: The role of B cells in cancer development, in the Journal: (JOURNAL)
- future: Simply depleting B cells couldn't well demonstrate the function of B cells in a specific tumor cell type thus further studies may be needed to elucidate which phenotype of B cells or which mechanism is predominant.
SUMMARY
Though the CD8+ T_cells have an irreplaceable role in the cytotoxicity in the tumor microenvironment (TME) and immune checkpoint inhibitors (ICIs) are quite efficient in many cancer . . .
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