The role of chronic liver diseases in the emergence and recurrence of hepatocellular carcinoma: an omics perspective

HIGHLIGHTS

  • who: Salvatore Piscuoglio from the Anatomic Unit, IRCCS Humanitas University Research Hospital, Milan, Italy, Visceral Surgery and Precision have published the paper: The Role of Chronic Liver Diseases in the Emergence and Recurrence of Hepatocellular Carcinoma: An Omics Perspective, in the Journal: (JOURNAL)
  • what: The molecular mechanisms underlying HCC tumorigenesis from a background of CLD are gradually being unveiled through recent sequencing efforts.
  • how: The data indicated that p53 exerted a cytostatic effect by blocking proliferation and triggering cellular senescence rendering cancer cells susceptible to recognition by the immune system .
  • future . . .

     

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