HIGHLIGHTS
- who: Mohsen Rokni from the (UNIVERSITY) have published the research work: The role of endothelin and RAS/ERK signaling in immunopathogenesis-related fibrosis in patients with systemic sclerosis: an updated review with therapeutic implications, in the Journal: (JOURNAL)
- what: The function of ET-1 and Ras in the pathogenesis of the dermis, lungs, or other organs fibrosis in SSc and other fibrotic diseases has been explored in several clinical and experimental studies.
- how: This review discusses the role of TGF-u03b2/ET-1/Ras signaling and their involvement in SSc pathogenesis particularly in . . .
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