The role of epigenetic modifications in neurotoxicity induced by neonatal general anesthesia

HIGHLIGHTS

  • who: Cheng-Hua Zhou and Yu-Qing Wu from the Jiangsu Province Key Laboratory of Anesthesiology, Xuzhou Medical University, Xuzhou, China, NMPA Key Laboratory for have published the research work: The Role of Epigenetic Modifications in Neurotoxicity Induced by Neonatal General Anesthesia, in the Journal: (JOURNAL)
  • how: The results showed that miR-124 inhibition strengthened glutamate receptors and upregulated PKC pathway after ketamine-exposure at postnatal 14 days which reversed the hippocampal neurodegeneration and improved memory loss.
  • future: Related studies that explored the role of it in the GA-induced neurotoxicity recently preferred . . .

     

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