The role of feedback loops in targeted therapy for pancreatic cancer

HIGHLIGHTS

  • who: Weigang Gu from the Department of Gastroenterology, Affiliated Hangzhou First People`s Hospital, Zhejiang University School of Medicine, Diseases of Zhejiang Province, Hangzhou, China have published the research: The Role of Feedback Loops in Targeted Therapy for Pancreatic Cancer, in the Journal: (JOURNAL)
  • what: The study showed that mutant-P53, unlike wildtype-P53, maintains STAT3 phosphorylation by replacing the phosphatase SHP2 .

SUMMARY

    Pancreatic cancer is the most common type malignant tumor with a high degree of malignancy and poor prognosis, which has now become a major medical dilemma and formidable . . .

     

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