HIGHLIGHTS
SUMMARY
Conditions improves the properties of MSCs (Khan et_al, 2011; Fan et_al, 2015). Hypoxia preconditioning has been proposed as an approach to improve the therapeutic potential of MSCs; in fact, it has been seen that short-term exposure to hypoxia has an empowering effect leading to increased cell migration and improved proliferation, survival, differentiation and paracrine activities of MSCs (Annabi et_al, 2003; Yang et_al, 2022). Human mesenchymal stromal cells (MSCs) possess the ability to self-renewal and multilinear differentiation (Minguell et_al, 2001; Pittenger and Martin, 2004) and have been isolated from different tissues such as . . .
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