HIGHLIGHTS
- who: PD- and colleagues from the Magna Gru00e6cia University of Catanzaro, Italy have published the paper: The role of immune checkpoints in cardiovascular disease, in the Journal: (JOURNAL)
- what: The authors aim to provide an overview of possible therapeutic targets in prevention or treatment of cardiovascular irAEs.
- future: The exact mechanisms behind the three ICI-mediated diseases atherosclerosis myocarditis and cardiomyopathy are not completely understood and future studies are warranted. More research focusing on downstream pathways of IC ligand host-cells such as the JAK/STAT MAP/Erk/mTOR PI3K/Akt pathways and . . .
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