The role of inflammatory cytokines in the pathogenesis of colorectal carcinoma—recent findings and review

HIGHLIGHTS

• who: Jędrzej Borowczak et al. from the Department of Perinatology, Gynaecology and Gynaecologic Oncology, Collegium Medicum, Department of Electroradiology, Poznan University of Medical Sciences, Poznań, Poland have published the article: The Role of Inflammatory Cytokines in the Pathogenesis of Colorectal Carcinoma—Recent Findings and Review, in the Journal: Biomedicines 2022, 1670 of /2022/
• how: A local initiation model was proposed in which local events such as tissue injury or 8 of 27 oncogenic mutations activate NF-κB and STAT3 cause the amplification of IL-6 signaling in non-immune cells and promote the secretion . . .
  

   

  

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