The role of phospholipase d in modulating the mtor signaling pathway in polycystic kidney disease

HIGHLIGHTS

• who: Yang Liu et al. from the Institute of Physiology, University of Zurich, Zürich, Switzerland, Center for Microscopy and Image Analysis, University of Zurich, Zürich, Switzerland have published the Article: The Role of Phospholipase D in Modulating the MTOR Signaling Pathway in Polycystic Kidney Disease, in the Journal: PLOS ONE | www.plosone.org of August/23,/2013
• what: The authors assessed in vitro the regulatory function of PLD and PA on the mTOR signaling pathway in PKD. The authors demonstrate that targeting mTOR did not induce autophagy whereas targeting PLD induced autophagosome formation . . .
  

   

  

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