The role of pkc/pkr in aging, alzheimer`s disease, and perioperative neurocognitive disorders

HIGHLIGHTS

  • who: Gordon Tin Chun Wong and Chunxia Huang from the Chinese Culture University, Taiwan have published the paper: The role of PKC/PKR in aging, Alzheimer`s disease, and perioperative neurocognitive disorders, in the Journal: (JOURNAL)
  • what: The authors provided compelling evidence that advanced age and surgery are associated with mitochondrial dysfunction and defective autophagy in both wild-type and 3u00d7Tg-AD mice.
  • how: The authors used wild-type transgenic AD mice to compare age-related changes in PKC/PKR expression and mitochondrial function. Data were analyzed with one-way ANOVA using Tukey . . .

     

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