The role of spastin in axon biology

HIGHLIGHTS

  • who: Ana Catarina Costa et al. from the University of Porto, Porto, Portugal, Graduate Program in Molecular and Cell, Instituto de Ciu00eancias Biomu00e9dicas Abel Germany have published the research work: The Role of Spastin in Axon Biology, in the Journal: (JOURNAL)
  • what: This work shows that spastin is important not only to maintain synapse density, but also to indirectly regulate synaptic transport through the maintenance of low polyglutamylated tubulin levels. This study shows that spastin affects the MTs surrounding the ER, impacting its morphology and function in neurons. This study shows that cultured neurons from . . .

     

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