HIGHLIGHTS
- who: Valentina Masola from the (UNIVERSITY) have published the research: The role of SPATA2 in TNF signaling, cancer, and spermatogenesis, in the Journal: (JOURNAL) of 11/Nov/2022
- what: More recently, using mass spectrometry and co-immunoprecipitation methods, four studies have made it possible to identify SPATA2 as the protein capable of binding CYLD on one side and HOIP on the other and, therefore, to be enrolled as a new component of the TNFR1 signaling complex. On the whole, the study showed that elevated TNF and SPATA2 mRNA expressions are independently associated with poor prognoses . . .
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