The role of the sirtuin family in cartilage and osteoarthritis: molecular mechanisms and therapeutic targets

HIGHLIGHTS

  • who: Kaibo Sun from the (UNIVERSITY) have published the article: The role of the sirtuin family in cartilage and osteoarthritis: molecular mechanisms and therapeutic targets, in the Journal: (JOURNAL)
  • what: With the precise mechanisms partly elucidated in recent studies, SIRT may represent good candidates for the treatment of OA.
  • future: Research is needed to verify whether SIRT3 directly targets TFAM in chondrocytes.

SUMMARY

    The progression of OA is also attributed to abnormal chondrocyte metabolism, and emerging evidence has revealed that OA and other metabolic diseases have common pathways, including . . .

     

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