The role of tripartite motif-containing 28 in cancer progression and its therapeutic potentials

HIGHLIGHTS

  • who: Yiqing Yang et al. from the Tangdu Hospital, China University of Kentucky, United States have published the Article: The role of tripartite motif-containing 28 in cancer progression and its therapeutic potentials, in the Journal: (JOURNAL)

SUMMARY

    To regulating gene transcription, TRIM28 has a variety of intracellular regulatory functions, including regulating the response to DNA damage and maintaining the stem_cell pluripotency. In Glioblastoma (GB), TRIM28 was also overexpressed in tumor stem_cells and associated with the expression of stem_cell-related genes. In conclusion, TRIM28 plays an important role in maintaining the pluripotent state . . .

     

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