HIGHLIGHTS
- who: Mcl- and colleagues from the Southern Medical University, China have published the research work: The roles of protocadherin-7 in colorectal cancer cells on cell proliferation and its chemoresistance, in the Journal: (JOURNAL)
- what: The authors characterized the abundance of PCDH7 in CRC cells correlated with their metastasis and chemoresistance. This study showed that MCL-1 expression was upregulated after P7 overexpression, and the related molecules of the Wnt/u03b2catenin pathway were also upregulated. The study provides strong evidence of the benefits of combining S63845 and ABT-263 for CRC, which is resistant to . . .
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