HIGHLIGHTS
- who: Johannes Werner and colleagues from the Division of Signaling and Functional Genomics, German Cancer Research Center (DKFZ), Medical Faculty Mannheim, Heidelberg University, Heidelberg, Germany have published the Article: The Roles of Secreted Wnt Ligands in Cancer, in the Journal: (JOURNAL)
- what: In this review, the authors provide an overview of the various roles WNTs play in tumorigenesis and tumor progression. In this model, increased invasiveness was shown to be dependent on JNK/AP-1 signaling. In this model, WNT5A was shown to increase the expression of CXCL5, which then reduced the infiltration of myeloid . . .
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