HIGHLIGHTS
- who: September and colleagues from the Jiangsu Ocean Universiity, China University of Toronto, Canada have published the article: The roles of the tumor suppressor para bromin in cancer, in the Journal: (JOURNAL)
- what: Genetic alteration of CDC73 and altered parafibromin expression both cause HPT-JT, parathyroid, gastric, colorectal, ovarian, lung, and head and neck carcinogenesis.
SUMMARY
In this review, the authors summarize the gene structure, biological functions, signaling pathways, and phenotypes of CDC73 knockout mice and the relationship of genetic and expression alterations in CDC73 with cancer. Parafibromin loss in PC . . .
If you want to have access to all the content you need to log in!
Thanks :)
If you don't have an account, you can create one here.