HIGHLIGHTS
- who: Feng Wang from the (UNIVERSITY) have published the research: The Saccharomyces cerevisiae Yta7 ATPase hexamer contains a unique bromodomain tier that functions in nucleosome disassembly, in the Journal: (JOURNAL) of November/19,/2022
- what: The study provides insights into nucleosome recognition and unfolding mechanism of Yta7 and contribute to understanding of the nucleosome disassembly. The work has shed new lights on the Yta7mediated nucleosome disassembly.
- how: For nucleosome-binding assay the authors used 50 nM 10xHis-3xFlag-Yta7 and 100 nM biotinylated human nucleosome. The reconstitution results were analyzed on 6% native . . .
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