HIGHLIGHTS
SUMMARY
Endometrial cancer (EC) is the fourth most common cause of cancer in women, with 10,013 new cases reported in Italy and 417,367 new cases reported worldwide in 2020. Recent analyses demonstrate significant improvement in overall survival (OS) and disease-free survival (DFS) in association with CT and RT versus RT alone, especially in stage III disease. The PORTEC-3 trial reported significant improvement in 5-year OS in stage III EC patients treated with CT plus RT versus RT alone (78.5% versus 68.5%, respectively; HR 0.63; p=0.043 . . .
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