HIGHLIGHTS
- who: Lilian Cristina Russo from the Department of Biochemistry, Institute of Chemistry, University of Su00e3o Paulo, Su00e3o Paulo, Brazil have published the paper: The SARS-CoV-2 Nsp3 macrodomain reverses PARP9/DTX3L-dependent ADP-ribosylation induced by interferon signaling, in the Journal: (JOURNAL) of July/16,/2021
- future: While further studies clearly required to clarify the role of and DTX3L in the response speculate differences in genetic manipulation of PARP9/DTX3L levels (overexpression CRISPR/Cas9 KO) cell types (fibrosarcoma macrophage retinal pigment epithelia) could account for differences.
SUMMARY
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