HIGHLIGHTS
- who: Minmin Zhang and colleagues from the College of Chemistry, Chemical Engineering and Biotechnology, Donghua University, Shanghai, China have published the research: The Second Class of Tetrahydrofolate (THF-II) Riboswitches Recognizes the Tetrahydrofolic Acid Ligand via Local Conformation Changes, in the Journal: (JOURNAL) of 25/03/2022
- what: The authors report switching models of the recently discovered acid-responsive second class of tetrahydrofolate riboswitches in response to binding. The experiments showed that tetrahydrofolic acid bound to the THF-II riboswitch and altered the conformation and flexibility of the RNA. This study investigated the ligand-free . . .
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