The selectivity of α‐adrenoceptor agonists for the human α1a, α1b, and α1d‐adrenoceptors

HIGHLIGHTS

• who: ERK et al. from the (UNIVERSITY) have published the research work: The selectivity of α‐adrenoceptor agonists for the human α1A, α1B, and α1D‐adrenoceptors, in the Journal: (JOURNAL)
• what: This study compared the binding affinity and functional responses of 62 compounds at the human α1A, α1B, α1D-­adrenoceptors. α1A and α1B-­adrenoceptors are present in human heart .
• future: Studies are required to determine whether ERK1/2-­phosphorylation in the study could be downstream from the low potency of these agonists are occurring at a lower affinity the calcium response (as suggested by_ . . .
  

   

  

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