The shaping of cancer genomes with the regional impact of mutation processes

HIGHLIGHTS

  • who: Soo-Youn Lee from the (UNIVERSITY) have published the research work: The shaping of cancer genomes with the regional impact of mutation processes, in the Journal: (JOURNAL) of 28/07/2022
  • what: The authors demonstrate that CCF-based mutation signatures can be delineated to show the time-scaled activity of various mutations.
  • how: The authors used whole-genome mutation profiles for 1925 cancer genomes available from International Cancer Genome Consortium (ICGC) to systematically analyze the mutation signatures of individual somatic mutations in cancer genomes12. Kataegis For Kataegis the authors used the R . . .

     

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