The significance of cell surface n-glycosylation for internalization and potency of cytotoxic conjugates targeting receptor tyrosine kinases

HIGHLIGHTS

• who: Marta Poźniak and colleagues from the Faculty of Biotechnology, Department of Protein Engineering, University of Wroclaw, Joliot-Curie, a have published the research work: The Significance of Cell Surface N-Glycosylation for Internalization and Potency of Cytotoxic Conjugates Targeting Receptor Tyrosine Kinases, in the Journal: (JOURNAL) of 27/06/2022
• what: The authors decided to assess the significance of cell surface N-glycosylation for the uptake and potency of CCs targeting model RTKs. The authors focused on two model RTKs that are overexpressed by several tumors: human epidermal growth factor receptor 2 (HER2 . . .
  

   

  

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