The size and conservation of a coiled-coil structure in the ectodomain of human bst-2/tetherin is dispensable for inhibition of hiv-1 virion release*

HIGHLIGHTS

  • who: Amy J. Andrew from the (UNIVERSITY) have published the article: The Size and Conservation of a Coiled-coil Structure in the Ectodomain of Human BST-2/Tetherin Is Dispensable for Inhibition of HIV-1 Virion Release*, in the Journal: (JOURNAL) of December/28,/2012
  • how: For consistency with immune recognition the authors utilized a BST-2 construct containing a triple HA tag downstream of residue 148 near the C terminus of the ectodomain as described previously . The functional properties of these BST-2 deletion mutants were tested in a virus release assay as described . . .

     

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