The small gtpases ras and rap1 bind to and control torc2 activity

HIGHLIGHTS

  • who: Ankita Khanna from the DepartmentUniversity of British Columbia, Vancouver, British Columbia V T , Canada have published the research work: The small GTPases Ras and Rap1 bind to and control TORC2 activity, in the Journal: Scientific Reports Scientific Reports
  • what: The authors propose that Rap1 positively regulates the RasC-mediated activation of TORC2 in response to chemoattractants. The authors propose that the dual RasC- and Rap1-mediated regulation of TORC2 in Dictyostelium allows for integration of RasC and Rap1 signaling pathways during chemotaxis and, thereby, coordination of cytoskeletal remodeling, substrate adhesion, and relay of the . . .

     

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