The steps to therapeutic drug monitoring: a structured approach illustrated with imatinib

HIGHLIGHTS

  • who: Thierry Buclin et al. from the Service Clinical Pharmacology, Department Laboratory Medicine and Pathology, Lausanne University Hospital (CHUV) and Lausanne University Hospital (CHUV) and University Lausanne (UNIL), Lausanne have published the article: The Steps to Therapeutic Drug Monitoring: A Structured Approach Illustrated With Imatinib, in the Journal: (JOURNAL)
  • how: The authors realized that the results were flawed by a significant lack of compliance among the prescribers with regard to the dosage adjustment propositions in the intervention group receiving routine TDM.

SUMMARY

    Model-based approaches advocated by visionary forerunners (Sheiner et_al . . .

     

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