The stimulation of inducible nitric-oxide synthase by the prion protein fragment 106⠍126 in human microglia is tumor necrosis factor-α-dependent and involves p38 mitogen-activated protein kinase*

HIGHLIGHTS

• who: Cinzia Fabrizi from the (UNIVERSITY) have published the research: The Stimulation of Inducible Nitric-oxide Synthase by the Prion Protein Fragment 106⠍126 in Human Microglia Is Tumor Necrosis Factor-α-dependent and Involves p38 Mitogen-activated Protein Kinase*, in the Journal: (JOURNAL) of April/20,/2001
• what: This study investigated the expression of the inducible form of the nitricoxide synthase (NOS-II) in human microglial cells treated with PrP-(106 -126). The authors report here that NF-␬B binding in PrP-treated microglial cells depends on the activation of p38 mitogen-activated protein kinase . . .
  

   

  

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