The strategies for treating “alzheimer’s disease“: insulin signaling may be a feasible target

HIGHLIGHTS

  • who: Guanying You and colleagues from the Shenzhen Key Laboratory of Marine Biotechnology and Ecology, College of Life Sciences and Oceanography, Shenzhen University, Shenzhen, China have published the Article: The Strategies for Treating ``Alzheimeru2019s Disease``: Insulin Signaling May Be a Feasible Target, in the Journal: (JOURNAL)
  • what: When using chemical methods to synthesize the phosphorylated K18 fragment (four microtubule-binding repeats), the study showed that the phosphorylation at S258, S262, and S356 dramatically reduced the aggregation and fibril seeding activity of K18 in_vitro . Based on the evidence collected, the authors propose that the insulin signaling . . .

     

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