HIGHLIGHTS
- who: Zhenshan Liu and collaborators from the Center for Immune-Related Diseases at Shanghai Institute of Immunology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China, Department of Immunology and Microbiology, Key have published the Article: The SUMO E3 ligase activity of ORF45 determines KSHV lytic replication, in the Journal: (JOURNAL) of April/28,/2022
- what: The work characterized as a novel virus encoded SUMO E3 ligase which is required for ORF45-RSK1 axis-mediated KSHV lytic gene expression.
- how: These results indicated that ORF45 is necessary and sufficient to promote . . .
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