The swr1 histone replacement complex causes genetic instability and genome-wide transcription misregulation in the absence of h2a.z

HIGHLIGHTS

  • who: The, SWR and Histone Replacement, Complex Causes from the Department of Molecular Biology, CABIMER-CSIC, Seville, Spain, Genomics Unit, CABIMER-CSIC, Seville, Spain have published the research work: The SWR1 Histone Replacement Complex Causes Genetic Instability and Genome-Wide Transcription Misregulation in the Absence of H2A.Z, in the Journal: (JOURNAL) of August/12,/2010
  • what: The authors show that instability sensitivity to drugs impairing different cellular processes and genome-wide transcriptional misregulation in htz1D can be partially or totally suppressed if is not formed (swr1D) if it forms but cannot bind to chromatin . . .

     

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