HIGHLIGHTS
- who: Oliver D. Howes from the environmental risk factors for the disorder, and new understanding on how synaptic loss could contribute to symptomsWe have revised the hypothesis to account for these new data. We call it version III, as we anticipate elements may need revision as further evidence accumulates. Notwithstanding this, it has the potential to explain a number of key aspects of the epidemiology and clinical expression of schizophrenia, including the peak age of onset and symptoms, and identifies mechanisms and new potential targets for treatment. Disclaimer The views expressed are those of the authors and . . .
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