The synthetic bacterial lipopeptide pam3csk4 modulates respiratory syncytial virus infection independent of tlr activation

HIGHLIGHTS

• who: D. Tien Nguyen et al. from the Department of Virology, Erasmus MC, University Medical Center, Rotterdam, The Netherlands, EMC microcollections GmbH, Tübingen, Germany, Academic Medical have published the article: The Synthetic Bacterial Lipopeptide Pam3CSK4 Modulates Respiratory Syncytial Virus Infection Independent of TLR Activation, in the Journal: (JOURNAL) of August/19,/2010
• what: The authors show that the effect of Pam3CSK4 is primarily mediated by enhanced binding of RSV to its target cells. The authors show that the non-TLR agonists Pam-Cys-SK4 and PHCSK4 are equally capable of enhancing HIV-1 infection . . .
  

   

  

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