The tgf- b /smad repressor tg-interacting factor 1 (tgif1) plays a role in radiation-induced intestinal injury independently of a smad signaling pathway

HIGHLIGHTS

  • who: Mohammad Hneino and collaborators from the Laboratory, British Columbia Cancer Agency and the University of British Columbia, Vancouver, British Columbia, Canada have published the Article: The TGF- b /Smad Repressor TG-Interacting Factor 1 (TGIF1) Plays a Role in Radiation-Induced Intestinal Injury Independently of a Smad Signaling Pathway, in the Journal: (JOURNAL) of March/22,/2012
  • what: The authors hypothesized that TGF-b1 signaling and target genes expression may depend on radiation-induced modifications in Smad transcriptional co-repressors/inhibitors expressions (TGIF1 SnoN Ski and Smad7). The authors demonstrate in_vivo in a model . . .

     

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