The therapeutic effect of fufang zhenshu tiaozhi (ftz) on osteoclastogenesis and ovariectomized-induced bone loss: evidence from network pharmacology, molecular docking and experimental validation

HIGHLIGHTS

• who: Xiaojun Chen and collaborators from the School of Molecular Sciences, University of Western Australia, Perth, Western Australia, Australia have published the research work: The therapeutic effect of Fufang Zhenshu Tiaozhi (FTZ) on osteoclastogenesis and ovariectomized-induced bone loss: evidence from network pharmacology, molecular docking and experimental validation, in the Journal: (JOURNAL)
• what: This bioinformatics analysis combined with the experimental verification study illustrated the potential effects of FTZ on suppressing osteoclastogenesis and bone loss induced by OVX, through regulating the cellular response to inflammation, myeloid cell and osteoclast differentiation, and TNF-α signaling pathway.
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