HIGHLIGHTS
- who: Sabrina Bimonte et al. from the Division of Abdominal Surgical Oncology, Hepatobiliary Unit, National Cancer Institute "GPascale Foundation" IRCCS, Naples, Italy have published the paper: The Therapeutic Targets of miRNA in Hepatic Cancer Stem Cells, in the Journal: (JOURNAL) of 18/Nov/2015
- what: In this review, we synthesize the latest findings on therapeutic regulation of miRNA by modulation of tumor-suppressive and oncogenic signaling pathways.
- how: Interesting data showed that Smad7 highly expressed in hepatocarcinoma and other types of cancer disease negatively regulates TGF-š¯›½ through Tš¯›½RI subunit or by interference . . .
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