The thermodynamic and kinetic aspects of midazolam ring closure from benzophenone to benzodiazepine form, its acid-base equilibria and aromaticity: a quantum-chemical study

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  • who: Wojciech Piotr Oziminski from the Department of Organic and Physical Chemistry, Faculty of Pharmacy, Medical University of Warsaw, Banacha Street, Warsaw, u2011097, Poland have published the Article: The thermodynamic and kinetic aspects of midazolam ring closure from benzophenone to benzodiazepine form, its acid-base equilibria and aromaticity: a quantum-chemical study, in the Journal: (JOURNAL)
  • what: The protonation sites for both midazolam and the model were also studied. The authors focus on two neutral (not cationic) forms of midazolam-open (MDZo) and closed (MDZ) which are depicted in Scheme 4. The aims of this . . .

     

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