The thermodynamics of pr55gag-rna interaction regulate the assembly of hiv

HIGHLIGHTS

  • who: Hanumant S. Tanwar and colleagues from the School of Medicine, Deakin University, Geelong, Australia, CSIRO Manufacturing, Parkville, Victoria have published the article: The thermodynamics of Pr55Gag-RNA interaction regulate the assembly of HIV, in the Journal: (JOURNAL) of February/21,/2017
  • what: The authors propose a model (Fig 5C) wherein many Pr55Gag molecules bind to GU-containing RNA in the cytosol forming low-order oligomers.
  • how: The results showed that the favourable enthalpy and Gibbs Free energy release from oligomerization can potentially be a general feature of RNA-Pr55Gag protein interaction during . . .

     

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