The toll-like receptor agonist imiquimod is active against prions

HIGHLIGHTS

  • who: The Toll-Like Receptor Agonist and collaborators from the Agronomique (INRA), Jouy-en-Josas, France, Department of Cell and Molecular Biology, BMC, Uppsala University, Uppsala, Sweden, Protein have published the research: The Toll-Like Receptor Agonist Imiquimod Is Active against Prions, in the Journal: PLOS ONE | www.plosone.org of August/16,/2013
  • how: To facilitate structure-activity relationship studies the authors conducted a new synthetic pathway which provides a more efficient means of producing new IQ chemical derivatives activity of which was tested against both yeast and mammalian prions. comparable antiprion activity of . . .

     

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