The toxoplasma effector gra28 promotes parasite dissemination by inducing dendritic cell-like migratory properties in infected macrophages

HIGHLIGHTS

• who: Arne L. ten Hoeve from the Department Stockholm University UMR5309, Universitu00e9 Grenoble Alpes, Grenoble, France have published the article: The Toxoplasma effector GRA28 promotes parasite dissemination by inducing dendritic cell-like migratory properties in infected macrophages, in the Journal: (JOURNAL)
• what: The authors report that upon T. gondii infection macrophages initiate the expression of transcription factors normally attributed to DCs upregulate CCR7 expression with a chemotactic response and perform systemic migration when adoptively transferred into mice. The authors show that parasite effector released by the MYR1 secretory pathway cooperates with host chromatin remodelers the . . .
  

   

  

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