The tradis toolkit: sequencing and analysis for dense transposon mutant libraries

HIGHLIGHTS

• who: Bioinformatics and colleagues from the University of Würzburg, Würzburg, Germany have published the paper: The TraDIS toolkit: sequencing and analysis for dense transposon mutant libraries, in the Journal: (JOURNAL)
• what: The authors provide tools for each step of analysis from the raw unaligned fastq files produced by the sequencer, through to predictions of gene essentiality and fitness effects.

SUMMARY

Steady improvements in high-throughput sequencing technologies have resulted in an increasing number of sequenced bacterial genomes, revealing extensive genetic diversity both within and between species. Transposon insertion sequencing . . .

 



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