The transcription factor egr-1 suppresses transformation of human fibrosarcoma ht1080 cells by coordinated induction of transforming growth factor-β1, fibronectin, and plasminogen activator inhibitor-1*

HIGHLIGHTS

• who: Chaoting Liu from the (UNIVERSITY) have published the research: The Transcription Factor EGR-1 Suppresses Transformation of Human Fibrosarcoma HT1080 Cells by Coordinated Induction of Transforming Growth Factor-β1, Fibronectin, and Plasminogen Activator Inhibitor-1*, in the Journal: (JOURNAL) of July/21,/1998
• what: The authors show that enhanced cell attachment contributes to the suppression via increased secretion of fibronectin (FN) and also of plasminogen activator inhibitor-1 (PAI-1). The experiments show that the complexes formed with the GST-EGR-1 preparation under the same conditions as with the FLAG-tagged-EGR-1 . . .
  

   

  

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