The transcription factor lef1 interacts with nfix and switches isoforms during adult hippocampal neural stem cell quiescence

HIGHLIGHTS

• who: July et al. from the Universidad Autu00f3noma Madrid, Spain have published the paper: The transcription factor LEF1 interacts with NFIX and switches isoforms during adult hippocampal neural stem cell quiescence, in the Journal: (JOURNAL)
• what: The authors provide further insight by showing that despite the increase in basal Wnt signalling, Q-NSPCs do not display a greater response to increasing GSK3B inhibition compared to A-NSPCs. The authors focused on 16 of these common upregulated genes that showed a LEF1 motif exclusively in the quiescence enhancer list . When the authors focused only on the . . .
  

   

  

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