The transcription factor promotes the d1 msn identity and represses the d2 msn identity

HIGHLIGHTS

  • who: ZFP and collaborators from the University of Calgary, Canada have published the paper: The transcription factor promotes the D1 MSN identity and represses the D2 MSN identity, in the Journal: (JOURNAL)
  • what: The authors focused the further analysis on the major cell types in the LGE at E14.5 . Previous work and the studies showed that Pou3f1, Isl1 and Zfhx3 are expressed in immature D1 MSNs (Ehrman et_al, 2013; Lu et_al, 2014; Zhang et_al, 2019).
  • how: The results showed that approximately 90% of BCL11B positive cells are ZFP503/BCL11B double-positive cells . . .

     

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