The transcriptional coactivator eya1 exerts transcriptional repressive activity by interacting with rest corepressors and rest-binding sequences to maintain nephron progenitor identity

HIGHLIGHTS

• who: The transcriptional coactivator Eya and collaborators from the Department of Genetics and Genomic Sciences, New York, NY, USA, Department of Neurosciences, New have published the Article: The transcriptional coactivator Eya1 exerts transcriptional repressive activity by interacting with REST corepressors and REST-binding sequences to maintain nephron progenitor identity, in the Journal: (JOURNAL)
• what: The authors combined transcriptomic, genomic, and proteomic approaches to characterize three aspects of Eya1: regulated genes, associated CREs and interacting proteins.
• how: The authors identified target genes associated cisregulatory elements and partner proteins. preferentially occupies promoter sequences and interacts . . .
  

   

  

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