The tumor suppressor htid1 inhibits stat5b activity via functional interaction*

HIGHLIGHTS

  • who: Isabelle Dhennin-Duthille from the (UNIVERSITY) have published the Article: The Tumor Suppressor hTid1 Inhibits STAT5b Activity via Functional Interaction*, in the Journal: (JOURNAL) of February/18,/2011
  • how: A similar experiment was conducted in the 697 pre-B cells which enabled the authors to demonstrate that IL-7-induced tyrosine phosphorylation of STAT5b was also associated with the loss of STAT5b and hTid1 interaction (Fig 3B). The authors showed that increasing amounts of hTid1 plasmids strongly inhibited STAT5b-induced and weakly affected STAT5a-induced luciferase activity. These data indicated that hTid1 preferentially and . . .

     

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